MRS.M. KAVITHA, AMRUTHA VARSHINI, Y. CHENNAKESHAVULU, M. SAI SRI, M. PRANEETH 03 03 Organ matching and transplantation are lifesaving medical procedures that require accurate donor recipient compatibility assessment to reduce rejection risks and improve transplant success rates However the current organ transplant system faces several challenges including inefficiencies in donorrecipient matching concerns about data security organ trafficking and limited transparency in allocation procedures Blockchain technology provides a decentralized secure and transparent solution to address these problems By using blockchain organ donation registries can be securely maintained ensuring that donor and recipient records remain tamperproof and reliable Smart contracts can automate the matching process based on predefined compatibility criteria improving efficiency and reducing waiting times for patients In addition blockchain technology improves traceability helping to prevent fraud and unethical activities in organ allocation This paper explores the integration of blockchain technology in organ matching and transplantation systems highlighting its potential to enhance data integrity increase transparency and streamline the transplant process ultimately improving trust among stakeholders and saving more lives Copyright (c) Journal of Science Engineering Technology and Management Science. All rights reserved 2026